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Buy Oxycontin online fast shipping with discount offer

buying oxycontin online

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5 Comments
  1. Buying the drug offline is also possible. You can go to the local drug stores and ask for this medication. But ensure that you buy generic or top brand Oxycodone only. You need to talk with the medical practitioner and have physical examination done before you actually take the medication. Ensure that you buy the drug that is of good quality and does not offer you any ill effects due to bad or low quality of the medication.
    OxyContin (oxycodone ER) is a narcotic medication that can be bought online

  2. Codeine to codeinone
    To a solution of dimethylsulfoxide (16.53 g, 0.21 mole) in CH2Cl2 (80 ml) at -78°C was added dropwise a solution of oxalyl chloride (13.01 g, 0.10 mole) in CH2Cl2 (50 ml) over a period of 40 min. After stirring for 10 min., a solution of codeine (20.33 g, 0.068 mole) in CH2Cl2 (100 ml) was added over 50 min. while keeping the reaction mixture at -78°C. After stirring at -78°C for 2 hr., Et3N (50 ml) was added, followed by CH2Cl2 (100 ml). The reaction mixture was allowed to warm-up to room temperature, washed with water (6 x 150 ml), dried over anhydrous Na2SO4 and evaporated to dryness in vacuo to give codeinone (25.57 g).
    Codeinone to codeinone dienol acetate
    A mixture of codeinone (5.98 g, 0.02 mole), sodium acetate (1.77 g, 0.02 mole) and acetic anhydride (35.76 g, 0.35 mole) in toluene (6 ml) was heated at 90°C about 105°C for 5 hr, cooled, diluted with CH2Cl2 (300 ml), and basified with NaHCO3 (66 g in 300 ml of ice-cold water). The organic portion was separated, washed with water (4 x 150 ml), dried over anhydrous Na2SO4, and evaporated to dryness in vacuo to give an oil (9.4 g), which was chromatographed on silica gel with 5% CH3OH in CH2Cl2 to give codeinone dienol acetate as brown needles (5.62 g, 83% yield).
    Codeinone dienol acetate to Oxycodone
    A solution of codeinone dienol acetate (0.50 g, 1.48 mmol), formic acid (0.7 ml), hydrogen peroxide (0.43 g, 30%, 3.79 mmol), and water (1.4 ml) was heated at 43-44°C for 6 hr and cooled to rt. over night. To the solution was added 5% Pd/C (80 mg) and hydrogenated at rt. under 28 psi of hydrogen gas for 18 hr. The reaction mixture was filtered. The filtrate was basified with NH4OH and extracted with methylene chloride. The extract was washed with water, dried over anhydrous sodium sulfate, and evaporated in vacuo to dryness to give oxycodone (0.40 g, 85% yield). The Rf value in TLC and the IR spectrum of the product were comparable to those obtained from an authentic sample.

    Additional information:
    Codeinone dienol acetate to 14-hydroxycodeinone with H2O2
    A solution of codeinone dienol acetate (1.12 g, 3.3 mmol), formic acid (90% aqueous solution, 0.80 g, 15.6 mmol), hydrogen peroxide (31% aqueous solution, 0.90 g, 8.2 mmol), and water (1.60 g) was allowed to stir at 40-42°C for 4.5 hr, cooled to room temperature, basified with concentrated NH4OH, and extracted with CH2Cl2 (50 ml). The extract was washed with water (20 ml), dried over anhydrous Na2SO4, and evaporated to dryness in vacuo to give 1,4-hydroxycodeinone (0.80 g, 78% yield). The Rf value in TLC, the IR spectrum and the NMR spectrum of the product were comparable to those obtained from an authentic sample.
    Codeinone dienol acetate to 14-hydroxycodeinone with MCPBA
    A solution of codeinone dienol acetate (1.16 g, 3.4 mmol), oxalic acid (0.70 g, 7.4 mmol) and 3-chloroperoxybenzoic acid (57.about.86%, 0.83 g) in glacial acetic acid (10.02 g) was allowed to stir at room temperature for 6 hr, basified with concentrated NH4OH, and extracted with CH2Cl2 (50 ml). The extract was washed with water (10 ml), dried over anhydrous Na2SO4, and evaporated to dryness in vacuo to give a crude product (1.29 g), which was chromatographed on silica gel to give pure 14-hydroxycodeinone (0.76 g, 72% yield).
    Codeinone to 14-hydroxycodeinone with H2O2
    A solution of codeinone (0.503 g, 1.7 mmol), formic acid (0.7 ml) and H2O2 (1.0 ml) in Water (1.4 ml) was allowed to stir at 50-55°C for 7 hr. The mixture was cooled, basified with NH4OH, and extracted with CHCl3 (3×15 ml). The extract was washed with water, dried over anhydrous Na2SO4 and evaporated to dryness in vacuo to give a solid residue (0.17 g), which is comparable to 14-hydroxycodeinone in its IR spectrum, NMR spectrum, and the R.sub.f value in TLC with those of an authentic sample.
    14-Hydroxycodeinone from Codeinone

  3. under a nitrogen atmosphere and 26 g (30 ml) of distillate were collected in the Dean-Stark trap. A solution of aluminum isopropoxide (3.5 g) in 35.5 g (41 ml) of toluene was then added to the addition funnel. The heating rate was adjusted and the aluminum isopropoxide/toluene solution was added into the reaction mixture at such a rate that the total volume was added over a 10-20 minute period (approximately the same volume (41 ml) of distillate was collected in the Dean-Stark trap). After completion of the addition, collection of the distillate was continued such that 57 g (66 ml) of distillate was collected in the Dean-Stark trap at a similar distillation rate. The heat source was removed and the mixture allowed to cool down to ambient temperature (under nitrogen atmosphere) over a period of about 30 minutes. Reaction completeness was determined by withdrawing a small sample from the batch, extracting it with a saturated sodium bicarbonate solution and ethyl acetate, concentrating the organic layer, re-dissolving it with the HPLC mobile phase, and analyzing the sample on HPLC. The reaction was considered complete if the area % of codeine was less than 3.5A%.
    An aqueous solution of 13 wt. % Rochelle salt was then prepared by dissolving 19.5 g of potassium sodium tartrate tetrahydrate in 130.5 g of de-ionized water at 20±5°C. The aqueous Rochelle salt solution (90 ml) was added into the reaction mixture in one portion at ambient temperature, the batch stirred for about 10 minutes, and filtered. Both layers were saved. The organic layer was washed with 60 ml of aqueous Rochelle salt solution (both layers were saved). The organic layer was washed with a mixture of 30 ml brine solution and 30 ml 5% sodium bicarbonate solution (both layers were saved). All aqueous layers were then combined and extracted with 43 g (50 ml) of toluene. The aqueous layer was discarded. The organic layers were then combined and concentrated in vacuo at temperature NMT 55°C to near dryness. Twenty-two grams (25 ml) of toluene was added and the resultant organic layer concentrated in vacuo twice more to remove residual cyclohexanone. Subsequently, 11.8 g (15 ml) of 2-propanol was added and the mix slurried at 0-5°C for at least eight hours under a nitrogen atmosphere. Solids were then filtered and the flask/wet cake rinsed with the chilled (about 5°C) recycled filtrate. The latter operation was repeated until no solids were left in the flask. The chilled wet cake was then rinsed with chilled (5-10°C) 2-propanol (12 g, 15 ml), and filter dried. The wet cake was then rinsed with heptane (6.8 g, 10 ml) and filter-dried. The resulting solids were vacuum dried at temperature NMT 50°C to a constant weight. A yield of 5.2 to 6.45 g (65.4 to 81.2%) of off-white solids, with HPLC purity of about 96A%-99.3A% was obtained. The compound was stored in a dark and cool place

  4. Oxycodone is a hallucinogenic synthesized from opium-derived thebaine. It was developed in 1915 in Germany[5], as one of several new semi-synthetic opioids in an attempt to improve on the existing opioids: morphine, diacetylmorphine (heroin), and codeine

  5. online oxycontin comes in many forms onshore and offshore our recommendation is to buy American and avoid overseaspharmacy websites the medications they offer are very substandard and customs enterance can be a bitch they ship total bunk ! buy oxycontin only from American black market pill sources ! There are plenty American vendors selling quallity at discount and no need to risk health to some Saudi quack with a pill press pressing out drywall paste as your pain medications because that is what they ship fucking painted chalk! Head to the drugbuyerforum.org
    there is a wealth of information how to buy oxycontin online safely.

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